Niltaz 4.5 Injection
Anti-infective
A combination antibiotic that treats a wide range of bacterial infections by killing microorganisms. Effective against infections of the ear, sinuses, throat, lungs, urinary tract, skin, joints, and bones.
Composition
| Active Ingredient | Strength |
|---|---|
| Piperacillin | 4000 mg |
| Tazobactam | 500 mg |
Packaging & Label Views
High-resolution views of packaging angles, blister details, and regulatory label markings.
View 1Primary Packshot & Front Panel
View 2Composition & Usage Details
View 3Packaging Warnings & Storage Specs
View 4Statutory Markings & Blister / Bottle
Uses
- Bacterial infections of the ear, sinuses, and throat
- Respiratory tract infections (pneumonia)
- Urinary tract infections
- Skin and soft tissue infections
- Bone and joint infections
Benefits
Broad-spectrum antibiotic coverage
Piperacillin is an extended-spectrum penicillin antibiotic effective against both gram-positive and gram-negative bacteria, including Pseudomonas aeruginosa.
Beta-lactamase inhibition
Tazobactam inhibits beta-lactamase enzymes produced by resistant bacteria, preventing them from breaking down piperacillin and expanding the range of organisms that can be treated.
Effective against resistant organisms
The combination is active against many bacteria that are resistant to standard penicillins, making it a valuable treatment for hospital-acquired and community infections.
How to Use
Administered by a healthcare professional only as an intravenous infusion. Do not self-administer. Complete the full prescribed course even if you feel better.
How It Works
Piperacillin is a penicillin-type antibiotic that kills bacteria by interfering with bacterial cell wall synthesis — specifically by binding to penicillin-binding proteins, preventing cross-linking of peptidoglycan chains and causing cell lysis. Tazobactam is a beta-lactamase inhibitor that binds to and irreversibly inhibits the beta-lactamase enzymes produced by resistant bacteria, protecting piperacillin from enzymatic degradation and restoring its antibacterial activity.
Side Effects
- Diarrhoea
- Nausea
- Vomiting
- Rash
- Injection site reactions (pain, redness, swelling)
This is not an exhaustive list. If you experience unexpected side effects, consult your doctor or report via our pharmacovigilance process.
Quick Tips
- Complete the full course of treatment even if symptoms improve early — stopping early can cause antibiotic resistance.
- Diarrhoea may occur during treatment. Probiotics may help; report bloody stools or severe abdominal cramps to your doctor.
- Stop this medicine and inform your doctor immediately if you develop an itchy rash, swelling of the face/throat/tongue, or breathing difficulty (signs of an allergic reaction).
Safety Advice
Safety Advice
No usual harmful interaction with alcohol at recommended doses.
No harmful effects observed in animal studies. Use only if prescribed by your doctor.
Unlikely to cause harm to the nursing infant at prescribed doses.
Effect on driving ability is not fully established. Exercise caution.
Dose adjustment may be needed in patients with kidney disease as piperacillin is renally excreted.
Dose adjustment is generally not required in patients with liver disease.
Rating key:
SafeSafe if PrescribedUse with CautionConsult Your DoctorUnsafeFact Box
- Habit Forming
- No
- Therapeutic Class
- Anti-infectives
Storage
Store below 30°C in a cool, dry place. Keep out of reach of children.
Manufacturer & Marketer Information
Marketed by
Avalin Laboratories Pvt Ltd
ASEB Road, Opp. ASTC Workshop, Ulubari, Guwahati, Assam 781007
Medical Disclaimer: The product information presented on this page is intended solely for healthcare professionals and patients under qualified medical supervision. It is not a substitute for professional clinical advice, diagnosis, or treatment. Prescription formulations must be used strictly in accordance with the direction of a licensed medical practitioner.
Adverse Event Reporting: If you suspect an adverse drug reaction or patient safety event related to this product, contact our pharmacovigilance unit at contact@avalinlaboratories.com or access our dedicated Pharmacovigilance Reporting Page.
Need more information about Niltaz 4.5 Injection?
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Avalin Laboratories Pvt Ltd — Official Product Monograph
Digital Reference: https://avalinlaboratories.com/products/niltaz-4-5-injection
Tata 1mg Third-Party Reference: https://www.1mg.com/drugs/niltaz-4.5-injection-1082686
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